I have a MikroTik RouterOS device that has some custom DNS settings and therefore I cannot change the DNS servers it provides to clients, which is a requirement to use UnoTelly or Unblockus. Instead I found the following article very helpful, it allows you to configure Conditional DNS forwarding for specific domains.
This works well because I use MediaHint to swap back and forth for NetFlix US and Canada, but use only the US Amazon Prime.
/ip firewall layer7-protocol add name=domain.com regexp=domain.com
/ip firewall mangle add chain=prerouting dst-address=<routeripaddress> layer7-protocol=domain.com action=mark-connection new-connection-mark=domain.com-forward protocol=tcp dst-port=53
/ip firewall mangle add chain=prerouting dst-address=<routeripaddress> layer7-protocol=domain.com action=mark-connection new-connection-mark=domain.com-forward protocol=udp dst-port=53
/ip firewall nat add action=dst-nat chain=dstnat connection-mark=domain.com-forward to-addresses=<UnoTellyDNSServerIPAddress>
/ip firewall nat add action=masquerade chain=srcnat connection-mark=domain.com-forward